Shimmer: detection of genetic alterations in tumors using next-generation sequence data
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چکیده
منابع مشابه
Shimmer: detection of genetic alterations in tumors using next-generation sequence data
MOTIVATION Extensive DNA sequencing of tumor and matched normal samples using exome and whole-genome sequencing technologies has enabled the discovery of recurrent genetic alterations in cancer cells, but variability in stromal contamination and subclonal heterogeneity still present a severe challenge to available detection algorithms. RESULTS Here, we describe publicly available software, Sh...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btt183